The causes and theories as to the physiology of chronic fatigue syndrome and fibromyalgia are very varied and generally not well known.

For this reason, the rationale for use of HBOT is just as varied.

Once again, this is an experimental use of the chamber. In general, patients with these conditions feel an over all better sense of well being, more energy, and less fatigability.

Decrease in pain sometimes occurs but is a more difficult and unreliable symptom to treat.